Improving the Lives of Rehabilitation Patients

Sensorimotor Studies

Short study name: Sensorimotor
Main inclusion criteria: Stroke onset less than 30 days
Main exclusion criteria: Active musculoskeletal or peripheral nerve disease that affects UE function; Deficits in communication or cognition
Brief description: A better understanding of sensorimotor behaviors early after stroke would enable clinicians to personalize rehabilitation care and to better match patients with an effective therapy.

Contact: Lorie Brinkman, Isabel Cardoso Ferreira, Andrea Stehman
Email: [email protected]

Telerehabilitation in the Home after Stroke

Short study name: TR-2 Trial Study
Main inclusion criteria: Age 18-80 years old; Index stroke radiographically verified; Time of onset 120+/30 days prior to randomization; Upper extremity deficits
Main exclusion criteria: A major, active, coexistent neurological or psychiatric disease, e.g., alcoholism or dementia; Deficits in communication that interfere with reasonable study participation
Brief description: Comprehensive video game-based arm motor therapy designed with the user's specific needs and goals in mind to increase dose of therapy

Contact: Ryan McCarville
Email: [email protected]

Telerehabilitation Bedside

Short study name: TR Bedside
Main inclusion criteria: Age 18 years or older; Individuals with arm weakness after a stroke, spinal cord injury or brain injury within 90 days of onset
Main exclusion criteria: A major, active, coexistent neurological or psychiatric disease; Deficits in cognitive status that will likely interfere substantially with playing assisted games or exercises; Deficits in communication that interfere with reasonable study participation 
Brief description: Video game based arm motor therapy

Contact: Michael Su; Isabel Cardoso Ferreira, Andrea Stehman
Email: [email protected]

Feasibility of Using Virtual Reality and Sensors

Short study name: Virtual Reality and Sensors
Main inclusion criteria: Stroke with right or left sided arm weakness and disability; Understand directions and able to provide feedback; Inpatients or outpatients
Main exclusion criteria: Other serious health conditions that would limit participation
Brief description: Use wearable sensor system and a virtual reality system to assist and give feedback about assessment and practice of a range of movement skills

Contact: Seungmin Jung or Bruce Dobkin, MD
Email: [email protected]

The Relationship Between Function, Stroke Severity and Perception of Health at Follow-up in Stroke Rehabilitation Patients

Short study name: PROMIS PRO
Main inclusion criteria: New onset stroke diagnosis; 18 years of age and older; Discharged from California Rehabilitation Institute between June 2019 and December 2020
Main exclusion criteria: Patients without new onset stroke; Under 18 years of age
Brief description: This retrospective study aims include determining the relationship between function, stroke severity and perceived health status in this population and the factors that predict favorable health status.

Contact: Maria Cecilia Alpasan
Email: [email protected]

The Efficacy of a Frequency-tuned Electromagnetic Field Treatment in Facilitating the Recovery of Subacute Ischemic Stroke Patients – a Pivotal Study

Short study name: EMAGINE-BrainQ 2.0
Main inclusion criteria: Age 22-80 inclusive; Ischemic stroke within 21 days; Arm weakness
Main exclusion criteria: Preexisting neurological conditions, including seizures
Brief description: BrainQ is an investigational wearable device that provide noninvasive electromagnetic fields to stimulate neuronal networks.  We are investigating to see if it can augment recovery after an ischemic stroke.

Contact: Michael Su or Pamela Roberts
Email: [email protected] or [email protected]

3D Kinematic Analysis of Human Movements

Short study name: 3D Kinematic Analysis
Main inclusion criteria: Patients with neurological disorders affecting their movements, as well as healthy controls
Main exclusion criteria: Patients who do not have any motor deficits will not be included in the study      
Brief description: Kinematic analysis, utilizing a stereo-camera system to video record human subjects as they perform arm movements.

Contact: Dr. Ahmet Arac
Email: [email protected]

ExaStimUpper Limb Pivotal Clinical Validation Study

Short study name: ExaStim
Main inclusion criteria: Chronic SCI between C2 and T2 inclusive; ASIA A,B, C or D; Limited function of UEs with ISNCSCI UE Motor score for each arm from 5 to 20 inclusive; Non-zero score in at least one of the UEMS C7, C8, and T1 muscles on either side
Main exclusion criteria: Active implanted medical device for electrical stimulation; Other internal metallic objectives; Botox injections to the upper limb in prior 3 months; Uncontrolled autonomic dysreflexia or orthostatic hypotension; BMI >40; Acute medical conditions under active treatment; Pregnant or planned pregnancy; Allergy to hydrogel, silicone, latex; Uncontrolled cardiopulmonary disease, ventilator dependent, uncontrolled epilepsy or seizures; Unmanaged depression, psychiatric disorders or ongoing substance abuse 
Brief description: To evaluate the effectiveness of the ExaStim device relative to sham stimulation in restoring upper extremity function in chronic SCI

Contact: Pamela Roberts
Email: [email protected]

COVID Recovered Inpatient Rehabilitation Outcomes

Short study name: COVID Recovered
Main inclusion criteria: First inpatient rehabilitation admission; 18 years of age and older; Diagnosis of Post-COVID-19
Main exclusion criteria: Under 18 years of age; Not first inpatient rehabilitation admission
Brief Description: This study will provide an analysis of COVID-19 patients treated within 12 inpatient rehabilitation facilities across the United States. This information will provide important evidence to guide inpatient rehabilitation facilities across a wide range of populations and geographic locations.

Contact: Pamela Roberts
Email: [email protected]

Pain Pre-Treatment Impact on Therapy Participation and Outcomes

Short study name: Pain
Main inclusion criteria: All admissions for orthopedic recovery during January – December 2022
Main exclusion criteria: Not admitted in CY 2022 for orthopedic conditions
Brief description: To better understand the effects of pain pre-treatment in the inpatient rehabilitation setting for orthopedic patients.

Contact: Brandi Hamilton
Email: [email protected]

Demographic and Clinical Characteristics of LVAD and Transplant Population and Association with Functional Gain in Self-care, Mobility, and Walking

Short study name: LVAD/Transplant
Main inclusion criteria: All transplant and LVAD patients 18 years old or older; Received LVAD implantation or organ transplant; Initial acute hospitalization; First inpatient rehabilitation after transplant or LVAD
Main exclusion criteria: Under 18 years of age; Subsequent admissions for transplant or LVAD
Brief description: To determine the demographic, encounter, and clinical characteristics of LVAD and transplant populations associated with functional gain in self-care, mobility, and walking and to determine if health equity had an impact on functional gain.

Contact: Pamela Roberts
Email: [email protected]